Living with migraines requires commitment and perseverance. Below is a selection of information and support for people with migraines.
Attention TOPAMAX Patients and Medical Professionals
Dispensing errors have been reported between TOPAMAX® (topiramate) tablets and Toprol-xl® (metoprolol succinate) extended-release tablets.
Please be sure to check your tablets to ensure you are taking the right medicine.
*Toprol-xl is a registered trademark of the AstraZeneca group of companies.
TOPAMAX® is approved for migraine prevention in adults
only.
TOPAMAX® is not used to stop a migraine after it
starts.
IMPORTANT SAFETY INFORMATION
Serious risks associated with TOPAMAX® include lowered bicarbonate
levels in the blood resulting in an increase in the acidity of the blood
(metabolic acidosis). Symptoms could include hyperventilation (rapid,
deep breathing), tiredness, loss of appetite, irregular heartbeat or
changes in the level of alertness. Call your doctor immediately if you
get these symptoms. Your doctor may want to do simple blood tests.
Chronic, untreated metabolic acidosis may increase the risk for kidney
stones or bone disease.
Like other antiepileptic drugs, TOPAMAX® may cause suicidal thoughts or
actions in a very small number of people, about 1 in 500. Pay attention
to any changes and call your doctor right away if you have any of these
symptoms, especially if they are new, worse, or worry you: thoughts
about suicide or dying, attempts to commit suicide, new or worse
depression, new or worse anxiety, feeling agitated or restless, panic
attacks, trouble sleeping, new or worse irritability, acting aggressive,
being angry, or violent, acting on dangerous impulses, an extreme
increase in activity and talking (mania) or other unusual changes in
behavior or mood.
Do not stop taking TOPAMAX® without first talking to your doctor.
Stopping TOPAMAX® suddenly can cause serious problems.
Other serious risks include decreased sweating, increased body
temperature, kidney stones, sleepiness, dizziness, confusion, difficulty
concentrating, and increased eye pressure (glaucoma). Call your doctor
immediately if you have any decrease in vision or eye pain. These
problems can lead to blindness if not treated right away.
More common side effects are tingling in arms and legs, loss of
appetite, tiredness, nausea, diarrhea, taste change and weight loss.
Tell your doctor about other medications you take.
You are encouraged to report negative side effects of prescription drugs
to the FDA. Visit
www.fda.gov/medwatch
, or call 1-800-FDA-1088.
Please
see full U.S. Prescribing Information.
© Ortho-McNeil-Janssen Pharmaceuticals, Inc. 2010. All rights reserved. Your use of the information on this site is subject to the terms of our Legal Notice. Please see our Privacy Policy. This site is published by Ortho-McNeil Neurologics, division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. which is solely responsible for its contents.
This information is intended for the use of our customers, patients and healthcare professionals in the United States and Puerto Rico only.
Ortho-McNeil-Janssen Pharmaceuticals, Inc. recognizes that the Internet is a global communications medium; however, laws, regulatory requirements and medical practices for pharmaceutical products vary from country to country. The prescribing information included here may not be appropriate for use outside the United States and Puerto Rico.
Capitalized product names are trademarks of Ortho-McNeil-Janssen Pharmaceuticals, Inc.
