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March 4, 2011 - FDA Drug Safety Communication: TOPAMAX® (topiramate) use during pregnancy can cause fetal harm, including an increased risk for cleft lip and/or cleft palate. For information from the company click here. The FDA announcement can be found at www.fda.gov.

About TOPAMAX® for Epilepsy

TOPAMAX® May Be Prescribed With Other Antiseizure Medicines

Even when other medicines haven't been working, TOPAMAX® may help control:

  • Partial-onset seizures
  • Primary generalized tonic-clonic seizures
  • Seizures associated with Lennox-Gastaut syndrome

If you are still having seizures while taking an antiseizure medicine, your healthcare professional may choose to add TOPAMAX® to your treatment.

How TOPAMAX® Can Help

Freedom From Seizures Is the Goal

TOPAMAX® has an established safety and efficacy profile and is a generally well-tolerated antiseizure medicine, proven to be effective in controlling a broad range of seizures in adults and children age 2 or older.

TOPAMAX® With Other Antiepileptic Drugs

Because TOPAMAX® works well with other medicines, it may also be prescribed along with another antiepileptic drug for patients who are still having seizures while taking the other treatment.

In combination with other antiepileptic drugs, TOPAMAX® has demonstrated efficacy in controlling seizures in adults and children age 2 or older who have:

  • Partial-onset seizures
  • Primary generalized tonic-clonic seizures
  • Seizures associated with Lennox-Gastaut syndrome

TOPAMAX® Used by Millions Since 1997

Since its introduction in the U.S. in 1997, TOPAMAX® has helped many people to achieve better control of their seizures. Other facts you should know about TOPAMAX® are listed below.

  • TOPAMAX® has an established safety profile.
  • TOPAMAX® is not associated with drug-induced weight gain.

TOPAMAX® May Be Right for You

Just as every person is different, so is every antiseizure medication. Because different people do not always respond in exactly the same way to the same medicine, you may need to try several medicines before you find the medicine (or combination of medicines) that does the best job of controlling your seizures with the fewest side effects. Your healthcare professional can work with you to find the treatment that is best for you.